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Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE building block Product Name DOTA-C4-azide Synonyms CAS

SKU 1612330123
4.2
USD495.00 USD539.00

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Description

Product Name DOTA-C4-azide Synonyms CAS Number n/a Related CAS Molecular Formula C20H36N8O7 Molecular Weight 500

Product Name Lissamine rhodamine B PEG3 azide Synonyms Sulforhodamine B PEG3 azide CAS Number N/A Related CAS Molecular Formula C35H46N6O9S2 Molecular Weight 758

This dye hass bright fluorescence

517 SMILES O=C1N(CC2=C1C=CC=C2NC1=NC(NC2=CC3=C(CCC3)C=C2)=NC=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE building block Product Name DOTA-C4-azide Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl

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