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BODIPY FL VH032 is a high-affinity fluorescent probe for the von Hippel–Lindau (VHL) protein
The biotinylated biomolecules can then be bound to avidin or streptavidin
Carboxylic acids of proteins and other water-soluble biopolymers can be coupled to this molecule in aqueous solution using water-soluble carbodiimides such as EDAC
Product Name Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C84H141N15O23 Molecular Weight 1729
Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg BODIPY FL VH032 is aSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly
