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Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB-PNP Synonyms CAS

SKU 15234587549
4.1
USD445.00 USD494.00

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Description

Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB-PNP Synonyms CAS Number Related CAS Molecular Formula C42H55N7O16 Molecular Weight 913

Product Name Pomalidomide-CO-C6-Br Synonyms Pomalidomide-4'-CO-C6-Br CAS Number n/a Related CAS Molecular Formula C20H22BrN3O5 Molecular Weight 464

Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB Synonyms CAS Number Related CAS Molecular Formula C38H55N9O11 Molecular Weight 813

Product Name: Cy3 carboxylic acid trisulfo Synonyms: Cy3 carboxylic acid

Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB-PNP Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker

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