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TMR-Sulfo-Halotag Ligand CAS Number Related CAS Molecular Formula C38H48ClN3O9S Molecular Weight 758
SiR-NHS is the NHS ester of SiR-6-COOH (652Ex/674Em) and can be conjugated to amine-containing molecules easily
Compared to earlier iterations
Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-MMAE sir TMR-Sulfo-Halotag Ligand CAS Number RelatedSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly
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