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DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg NCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%

SKU 11322109109
4.9
USD495.00 USD538.00

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Description

NCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

3-triazole linkages

1957235-75-4 (TFA salt) Molecular Formula C21H27ClN4O8 Molecular Weight 498

can be hydrolyzed by intracellular esterases to release the fluorescent fluorescein core

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:25mg NCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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