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Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:1mg Journal of Medicinal Chemistry 2022

Description

Journal of Medicinal Chemistry 2022

Product Name: Lenalidomide-5'-CO-C1-amine HCl Synonyms: CAS Number: n/a Molecular Formula: C15H17ClN4O4 Molecular Weight: 352

325 SMILES OCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

364 SMILES OCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:1mg Journal of Medicinal Chemistry 2022SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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