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Subsequent functional enrichment analysis of these continuously upregulated and downregulated DhMRs revealed that upregulated DhMRs were primarily associated with regulation of fatty acid transport, response to transforming growth factor beta, and regulation of lipid catabolic process, while downregulated DhMRs were mainly linked to positive regulation of leukocyte differentiation, myeloid leukocyte differentiation, sensory system development, and stem cell development [Figure 4C]

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